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http://purl.uniprot.org/citations/8175692http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8175692http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8175692http://www.w3.org/2000/01/rdf-schema#comment"A 160-kDa plasma membrane protein of the yeast Saccharomyces cerevisiae was overexpressed by mutating the PDR1 or the PDR3 transcription factor gene. The protein is the membrane-bound ATP binding cassette transporter PDR5 (Balzi, E., Wang, M., Leterme, S., Van Dyck, L., and Goffeau, A. (1994) J. Biol. Chem. 269, 2206-2214). PDR5 was solubilized with n-dodecyl-beta-D-malto-side and separated from the PMA1 plasma membrane H(+)-ATPase by glycerol gradient centrifugation. The PDR5 protein hydrolyzes nucleoside diphosphates and triphosphates. This activity is sensitive to low concentrations of vanadate, of oligomycin, and of a variety of hydrophobic compounds. Many of these properties liken PDR5 to the purified mammalian P-glycoprotein responsible for multidrug resistance."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(18)99946-1"xsd:string
http://purl.uniprot.org/citations/8175692http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(18)99946-1"xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/author"Goffeau A."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/author"Goffeau A."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/author"Balzi E."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/author"Balzi E."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/author"Decottignies A."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/author"Decottignies A."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/author"Kolaczkowski M."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/author"Kolaczkowski M."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/pages"12797-12803"xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/pages"12797-12803"xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/title"Solubilization and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/title"Solubilization and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast."xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/volume"269"xsd:string
http://purl.uniprot.org/citations/8175692http://purl.uniprot.org/core/volume"269"xsd:string
http://purl.uniprot.org/citations/8175692http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8175692
http://purl.uniprot.org/citations/8175692http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8175692