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http://purl.uniprot.org/citations/8178173http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8178173http://www.w3.org/2000/01/rdf-schema#comment"A gene involved in psoriasis susceptibility was localized to the distal region of human chromosome 17q as a result of a genome-wide linkage analysis with polymorphic microsatellites and eight multiply affected psoriasis kindreds. In the family which showed the strongest evidence for linkage, the recombination fraction between a psoriasis susceptibility locus and D17S784 was 0.04 with a maximum two-point lod score of 5.33. There was also evidence for genetic heterogeneity and although none of the linked families showed any association with HLA-Cw6, two unlinked families showed weak levels of association. This study demonstrates that in some families, psoriasis susceptibility is due to variation at a single major genetic locus other than the human lymphocyte antigen locus."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.org/dc/terms/identifier"doi:10.1126/science.8178173"xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/author"Young M."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/author"Barnes R."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/author"Silverman A."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/author"Menter A."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/author"Wuepper K.D."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/author"Fernandez-Vina M.A."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/author"Stastny P."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/author"Morris L."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/author"Lory D."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/author"Tomfohrde J."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/pages"1141-1145"xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/title"Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q."xsd:string
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/volume"264"xsd:string
http://purl.uniprot.org/citations/8178173http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8178173
http://purl.uniprot.org/citations/8178173http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8178173
http://purl.uniprot.org/citations/8178173http://purl.uniprot.org/core/authorsIncomplete"true"xsd:boolean
http://purl.uniprot.org/uniprot/#_A8K4G0-mappedCitation-8178173http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8178173
http://purl.uniprot.org/uniprot/#_Q86YW5-mappedCitation-8178173http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8178173
http://purl.uniprot.org/uniprot/#_Q9NP99-mappedCitation-8178173http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8178173
http://purl.uniprot.org/uniprot/#_O95944-mappedCitation-8178173http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8178173