| http://purl.uniprot.org/citations/8181059 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8181059 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8181059 | http://www.w3.org/2000/01/rdf-schema#comment | "We describe a universal ligand-binding receptor for human interferons alpha and interferon beta (type I IFNs). A soluble 40 kDa IFN-alpha/beta receptor (p40) that blocks the activity of type I IFNs was purified from urine and sequenced. Antibodies raised against p40 completely block the activity of several type I IFNs and immuno-precipitate both a cellular 102 kDa IFN-alpha/beta receptor and its cross-linked complexes with IFN-alpha 2. The receptor is a disulfide-linked dimer, consisting of 51 kDa subunits. We isolated and expressed a 1.5 kb cDNA, coding for the IFN-alpha/beta receptor. Its 331 amino acid sequence includes a leader and a transmembrane region, while its ectodomain corresponds to p40. IFN-alpha/beta receptor is physically associated with the cytoplasmic Tyr kinase JAK1, hence, in addition to ligand binding, it is directly involved in signal transduction."xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(94)90154-6"xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(94)90154-6"xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/author | "Novick D."xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/author | "Novick D."xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/author | "Rubinstein M."xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/author | "Rubinstein M."xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/author | "Cohen B."xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/author | "Cohen B."xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/pages | "391-400"xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/pages | "391-400"xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/title | "The human interferon alpha/beta receptor: characterization and molecular cloning."xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/title | "The human interferon alpha/beta receptor: characterization and molecular cloning."xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/volume | "77"xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://purl.uniprot.org/core/volume | "77"xsd:string |
| http://purl.uniprot.org/citations/8181059 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8181059 |
| http://purl.uniprot.org/citations/8181059 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8181059 |
| http://purl.uniprot.org/citations/8181059 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8181059 |
| http://purl.uniprot.org/citations/8181059 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8181059 |