http://purl.uniprot.org/citations/8183572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8183572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8183572 | http://www.w3.org/2000/01/rdf-schema#comment | "We have identified a novel protein kinase, designated MLK-3, from human thymus using RT-PCR and cDNA library screening. The deduced open reading frame, derived from sequencing a 3.5 kb MLK-3 cDNA, encodes a protein of 847 amino acids with several interesting structural features. These include an SH3 domain in the absence of an SH2 domain, a region containing two leucine zippers with an adjacent carboxy-terminal basic region, and a proline rich region. This kinase shows homology with the mixed-lineage family of protein kinases (MLK) and shares the unusual leucine zipper-basic motif found in previously identified MLK kinases. By northern analysis, MLK-3 mRNA was detected in a wide variety of normal and transformed human cell lines and tissue specimens. The gene encoding MLK-3 has been mapped using fluorescence in situ hybridization to human chromosome 11 q13.1-13.3, a region frequently altered in human malignancies."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/author | "Tsui L.-C."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/author | "Tsui L.-C."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/author | "Heng H.H.Q."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/author | "Heng H.H.Q."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/author | "Ing Y.L."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/author | "Ing Y.L."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/author | "Lassam N.J."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/author | "Lassam N.J."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/author | "Leung I.W.L."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/author | "Leung I.W.L."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/pages | "1745-1750"xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/pages | "1745-1750"xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/title | "MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/title | "MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain."xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/volume | "9"xsd:string |
http://purl.uniprot.org/citations/8183572 | http://purl.uniprot.org/core/volume | "9"xsd:string |
http://purl.uniprot.org/citations/8183572 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8183572 |
http://purl.uniprot.org/citations/8183572 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8183572 |