http://purl.uniprot.org/citations/8200349 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8200349 | http://www.w3.org/2000/01/rdf-schema#comment | "The NAM1 nuclear gene was shown to control the stability and/or processing of mitochondrial transcripts of the cytochrome b, cytochrome oxidase subunit I and ATP synthase subunit VI genes [Groudinsky O., Bousquet I., Wallis M. G., Slonimski, P. P. & Dujardin G. (1993) Mol. Gen. Genet. 240, 419-427]. In order to better understand the mode of action of the NAM1 gene product, we have examined its intracellular fate. A fusion plasmid enabling bacterial over-expression of the corresponding protein-A-NAM1 cognate was constructed and subsequently employed as an antigen to raise polyclonal antibodies. These antibodies specifically recognise a 50-kDa protein which purifies along with the mitochondria and corresponds to NAM1p. Submitochondrial localisation experiments show that NAM1p is a soluble protein, located interior to the mitoplasts. Matricial location is a strong argument in favour of a direct interaction of NAM1p with particular mitochondrial transcripts and leads us to propose a model in which NAM1p could be an RNA-convoying protein stabilising and directing mitochondrial transcripts towards the inner face of the inner membrane where translation and assembly seem to occur."xsd:string |
http://purl.uniprot.org/citations/8200349 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1432-1033.1994.tb18837.x"xsd:string |
http://purl.uniprot.org/citations/8200349 | http://purl.uniprot.org/core/author | "Dujardin G."xsd:string |
http://purl.uniprot.org/citations/8200349 | http://purl.uniprot.org/core/author | "Slonimski P.P."xsd:string |
http://purl.uniprot.org/citations/8200349 | http://purl.uniprot.org/core/author | "Groudinsky O."xsd:string |
http://purl.uniprot.org/citations/8200349 | http://purl.uniprot.org/core/author | "Wallis M.G."xsd:string |
http://purl.uniprot.org/citations/8200349 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8200349 | http://purl.uniprot.org/core/name | "Eur J Biochem"xsd:string |
http://purl.uniprot.org/citations/8200349 | http://purl.uniprot.org/core/pages | "27-32"xsd:string |
http://purl.uniprot.org/citations/8200349 | http://purl.uniprot.org/core/title | "The NAM1 protein (NAM1p), which is selectively required for cox1, cytb and atp6 transcript processing/stabilisation, is located in the yeast mitochondrial matrix."xsd:string |
http://purl.uniprot.org/citations/8200349 | http://purl.uniprot.org/core/volume | "222"xsd:string |
http://purl.uniprot.org/citations/8200349 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8200349 |
http://purl.uniprot.org/citations/8200349 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8200349 |
http://purl.uniprot.org/uniprot/P10849#attribution-ECAFF980E881CFA98FC66A1B1C4FDBB5 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/8200349 |
http://purl.uniprot.org/uniprot/#_P10849-mappedCitation-8200349 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8200349 |
http://purl.uniprot.org/uniprot/P10849 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/8200349 |