http://purl.uniprot.org/citations/8207122 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8207122 | http://www.w3.org/2000/01/rdf-schema#comment | "To investigate the potential role of cytokines in the development of the central nervous system, we analyzed the production of cytokine mRNA transcripts by S1-nuclease protection analysis in the brains of Swiss-Webster mice during fetal development and after birth. Cytokines studied were interleukin (IL)-1 alpha, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, macrophage-colony stimulating factor (M-CSF), granulocyte-colony stimulating factor (G-CSF), granulocyte macrophage-colony stimulating factor (GM-CSF), and leukemia inhibitory factor (LIF). Only mRNA transcripts for M-CSF were found to be produced constitutively in normal brain tissue. These transcripts were detected continuously from embryonic day (ED) 13 through adulthood. Transcripts encoding the M-CSF receptor (c-fms) were also detected at all of these time points. Despite identification of M-CSF transcripts in the brains of normal mice during development and M-CSF protein in cell cultures, neuropathological examination of the brains of op/op mice, a naturally occurring mouse mutant defective in the production of functional M-CSF, showed no cytoarchitectural abnormalities."xsd:string |
http://purl.uniprot.org/citations/8207122 | http://purl.org/dc/terms/identifier | "doi:10.1016/0165-5728(94)90156-2"xsd:string |
http://purl.uniprot.org/citations/8207122 | http://purl.uniprot.org/core/author | "Chang Y."xsd:string |
http://purl.uniprot.org/citations/8207122 | http://purl.uniprot.org/core/author | "Lee F."xsd:string |
http://purl.uniprot.org/citations/8207122 | http://purl.uniprot.org/core/author | "Albright S."xsd:string |
http://purl.uniprot.org/citations/8207122 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8207122 | http://purl.uniprot.org/core/name | "J Neuroimmunol"xsd:string |
http://purl.uniprot.org/citations/8207122 | http://purl.uniprot.org/core/pages | "9-17"xsd:string |
http://purl.uniprot.org/citations/8207122 | http://purl.uniprot.org/core/title | "Cytokines in the central nervous system: expression of macrophage colony stimulating factor and its receptor during development."xsd:string |
http://purl.uniprot.org/citations/8207122 | http://purl.uniprot.org/core/volume | "52"xsd:string |
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