| http://purl.uniprot.org/citations/8223561 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8223561 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8223561 | http://www.w3.org/2000/01/rdf-schema#comment | "Three cDNA clones encoding small GTP-binding proteins, LS-Rab1, LS-Rab2 and LS-Rab18a were isolated from a cDNA library from the albumen gland of the pulmonate snail Lymnaea stagnalis. Comparison of the deduced amino acid sequences with available sequences from the EMBL/Data Bank revealed that LS-Rab1 and LS-Rab2 show a sequence identity of 89-90% to the mammalian Rab1 and Rab2 proteins, and can therefore be regarded as the L. stagnalis homologs. LS-Rab18a may be considered a new member of the Rab subfamily, closely related to mouse Rab18 (74% amino acid identity). Interestingly, LS-Rab1 and LS-Rab2 share a very high sequence conservation with their mammalian homologs (95-97%) over the first 178-191 N-terminal amino acids, whereas the C-terminal part is almost completely divergent, except for their extreme ends (2-4 amino acids). The implications of these observations for the understanding of Rab-targeting signals are discussed. The LS-rab cDNAs were expressed in COS-7M6 cells. The resulting 22-kDa products were shown to bind GTP. In the albumen gland mRNA, levels of LS-rab1 appeared to be much higher than those of LS-rab2 and LS-rab18a, suggesting an important role for the LS-Rab1 protein in the albumen gland."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1432-1033.1993.tb18239.x"xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1432-1033.1993.tb18239.x"xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "Yang H."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "Yang H."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "Ploegh H.L."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "Ploegh H.L."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "Agterberg M."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "Agterberg M."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "van Die I."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "van Die I."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "van den Eijnden D.H."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "van den Eijnden D.H."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "van Tetering A."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "van Tetering A."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "Andriessen J.A."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/author | "Andriessen J.A."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/name | "Eur. J. Biochem."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/name | "Eur. J. Biochem."xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/pages | "241-246"xsd:string |
| http://purl.uniprot.org/citations/8223561 | http://purl.uniprot.org/core/pages | "241-246"xsd:string |