| http://purl.uniprot.org/citations/8226690 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8226690 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8226690 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/8226690 | http://www.w3.org/2000/01/rdf-schema#comment | "Studies with cell-free protein preparations from a series of recombinant strains of Pseudomonas denitrificans demonstrated that precorrin-3 is converted into a further trimethylated intermediate, named precorrin-3B, along the pathway to coenzyme B12. It was then shown that the part of the pathway from precorrin-3 (called precorrin-3A hereafter) to precorrin-6x involves three intermediates, precorrin-3B, precorrin-4, and precorrin-5. Precorrin-3B was isolated in its native (reduced) as well as its oxidized (factor-IIIB) states, and precorrin-4 was isolated in its oxidized form only (factor-IV). Both factors were in vitro precursors of precorrin-6x. The synthesis of precorrin-6x from precorrin-3A was shown to be catalyzed by four enzymes, CobG, CobJ, CobM, and CobF, intervening in this order. They were purified to homogeneity. CobG, which converts precorrin-3A to precorrin-3B, was found to be an iron-sulfur protein responsible for the oxidation known to occur between precorrin-3A and precorrin-6x, and CobJ, CobM, and CobF are the C-17, C-11, and C-1 methylases, respectively. The acetate fragment is extruded after precorrin-4 formation. This study combined with our recent structural studies on factor-IV (D. Thibaut, L. Debussche, D. Fréchet, F. Herman, M. Vuilhorgne, and F. Blanche, J. Chem. Soc. Chem. Commun. 1993:513-515, 1993) and precorrin-3B (L. Debussche, D. Thibaut, M. Danzer, F. Debu, D. Fréchet, F. Herman, F. Blanche, and M. Vuilhorgne, J. Chem. Soc. Chem. Commun. 1993:1100-1103, 1993) provides a first step-by-step picture of the sequence of the enzymatic reactions leading to the corrin ring in P. denitrificans."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.175.22.7430-7440.1993"xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.175.22.7430-7440.1993"xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/author | "Crouzet J."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/author | "Crouzet J."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/author | "Debussche L."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/author | "Debussche L."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/author | "Thibaut D."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/author | "Thibaut D."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/author | "Blanche F.J."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/author | "Blanche F.J."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/author | "Cameron B."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/author | "Cameron B."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/pages | "7430-7440"xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/pages | "7430-7440"xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/title | "Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/title | "Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans."xsd:string |
| http://purl.uniprot.org/citations/8226690 | http://purl.uniprot.org/core/volume | "175"xsd:string |