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http://purl.uniprot.org/citations/8247000http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8247000http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8247000http://www.w3.org/2000/01/rdf-schema#comment"Transcription initiation factor TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. To further understand the role of the 85-kDa TFIID subunit (p85), we have cloned the corresponding cDNA with a probe based on an amino acid sequence of the purified protein. The recombinant p85 interacts directly with both the TATA box-binding subunit (TFIID tau or TBP) and the 110-kDa subunit (p110) of TFIID, suggesting that p85 may play a role in helping to anchor p110 within the TFIID complex and, with other studies, that TFIID assembly and function may involve a concerted series of subunit interactions. Interestingly, the carboxy terminus of p85 contains eight of the WD-40 repeats found originally in the beta subunit of G proteins and more recently in other transcriptional regulatory factors. However, truncated p85 lacking all the WD-40 repeats maintained interactions with both TFIID tau and p110. These observations leave open the possibility of a distinct function for the WD-40 repeats, possibly in transducing signals by interactions with transcriptional regulators and/or other components of the basic transcriptional machinery."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.org/dc/terms/identifier"doi:10.1128/mcb.13.12.7859-7863.1993"xsd:string
http://purl.uniprot.org/citations/8247000http://purl.org/dc/terms/identifier"doi:10.1128/mcb.13.12.7859-7863.1993"xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Yamashita S."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Yamashita S."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Nakatani Y."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Nakatani Y."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Horikoshi M."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Horikoshi M."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Kokubo T."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Kokubo T."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Roeder R.G."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Roeder R.G."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Gong D.-W."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Gong D.-W."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Takada R."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/author"Takada R."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/name"Mol. Cell. Biol."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/name"Mol. Cell. Biol."xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/pages"7859-7863"xsd:string
http://purl.uniprot.org/citations/8247000http://purl.uniprot.org/core/pages"7859-7863"xsd:string