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http://purl.uniprot.org/citations/8259676http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8259676http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8259676http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8259676http://www.w3.org/2000/01/rdf-schema#comment"The herpes simplex virus type 1 (HSV-1) tegument protein VP16 is a potent transcriptional inducer of immediate-early gene expression, comprising an N-terminal domain involved in binding DNA linked to an acidic transactivating C-terminal domain. The gene encoding the counterpart of this protein in equid herpesvirus 4 (EHV-4) was sequenced. Comparisons with VP16 and the homologous proteins of equine herpesvirus 1 (EHV-1) and varicella-zoster virus (VZV) showed that a region in the N-terminal domain involved in formation of a complex with cellular proteins is partially conserved in all four proteins. In contrast, the C-terminal regions of the EHV proteins, like that of VZV, are not particularly acidic and are not significantly conserved with respect to the C-terminal region of VP16. Nevertheless, transient expression experiments indicated that the EHV-1 and EHV-4 proteins are able to transactivate HSV-1 and EHV-1 immediate-early promoters in a dose-dependent manner, which suggests that this activity is not dependent on an acidic C-terminal domain."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.org/dc/terms/identifier"doi:10.1006/viro.1994.1047"xsd:string
http://purl.uniprot.org/citations/8259676http://purl.org/dc/terms/identifier"doi:10.1006/viro.1994.1047"xsd:string
http://purl.uniprot.org/citations/8259676http://purl.org/dc/terms/identifier"doi:10.1006/viro.1994.1047"xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Davison A.J."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Davison A.J."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Davison A.J."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Telford E.A."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Telford E.A."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Telford E.A."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Riggio M.P."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Riggio M.P."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Allsopp R."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Allsopp R."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Allsopp R."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Azam S."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Azam S."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Azam S."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Edington N."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Edington N."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Edington N."xsd:string
http://purl.uniprot.org/citations/8259676http://purl.uniprot.org/core/author"Purewal A.S."xsd:string