| http://purl.uniprot.org/citations/8264149 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8264149 | http://www.w3.org/2000/01/rdf-schema#comment | "Regulation of erythropoietin production by the kidneys is central to the control of erythropoiesis. Uncertainty about the identity of the renal cells involved has been a major obstacle to understanding this mechanism. We have used sequence from the mouse erythropoietin locus to direct expression of a marker gene, SV40 T antigen, to these cells in transgenic mice. The transgenic constructs contained an oligonucleotide marker (Epo-M) or SV40 sequence (Epo-TAg) in the 5' untranslated region of the mouse erythropoietin gene, flanked on each side by 9 and 7.5 kb of DNA from the mouse erythropoietin locus. Anemia-inducible expression of Epo-M and Epo-TAg was observed in the kidney. In one of thirteen lines, homologous integration of Epo-TAg into the mouse erythropoietin locus occurred. In transgenic mice bearing Epo-TAg at homologous and heterologous insertion sites, renal expression was restricted to a population of cells in the interstitium of the cortex and outer medulla. Immunohistochemical characterization by light and electron microscopy shows that these are the fibroblast-like type I interstitial cells."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.org/dc/terms/identifier | "doi:10.1038/ki.1993.362"xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/author | "Ferguson D.J."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/author | "Ratcliffe P.J."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/author | "Tan C.C."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/author | "Maxwell P.H."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/author | "Pugh C.W."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/author | "Johnson M.H."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/author | "Nicholls L.G."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/author | "Doe B.G."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/author | "Heryet A."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/author | "Osmond M.K."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/name | "Kidney Int"xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/pages | "1149-1162"xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/title | "Identification of the renal erythropoietin-producing cells using transgenic mice."xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://purl.uniprot.org/core/volume | "44"xsd:string |
| http://purl.uniprot.org/citations/8264149 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8264149 |
| http://purl.uniprot.org/citations/8264149 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8264149 |
| http://purl.uniprot.org/uniprot/#_Q0VED9-mappedCitation-8264149 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8264149 |
| http://purl.uniprot.org/uniprot/#_B7ZMY9-mappedCitation-8264149 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8264149 |
| http://purl.uniprot.org/uniprot/#_P07321-mappedCitation-8264149 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8264149 |
| http://purl.uniprot.org/uniprot/P07321 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/8264149 |
| http://purl.uniprot.org/uniprot/Q0VED9 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/8264149 |