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http://purl.uniprot.org/citations/8319294http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8319294http://www.w3.org/2000/01/rdf-schema#comment"Primary gene amplification, i.e., mutation from one gene copy to multiple gene copies per genome, is important in genomic evolution, as a means of producing anti-cancer drug resistance, and is associated with the progression of tumor malignancy. Primary amplification has not been studied in normal eukaryotic cells because amplifications are extremely rare in these cells. A system has been developed to phenotypically identify co-amplifications of the ADH4 and CUP1 genes of Saccharomyces cerevisiae and 21 independent spontaneous amplifications have been isolated."xsd:string
http://purl.uniprot.org/citations/8319294http://purl.org/dc/terms/identifier"doi:10.1007/bf00312624"xsd:string
http://purl.uniprot.org/citations/8319294http://purl.uniprot.org/core/author"Paquin C.E."xsd:string
http://purl.uniprot.org/citations/8319294http://purl.uniprot.org/core/author"Dorsey M.J."xsd:string
http://purl.uniprot.org/citations/8319294http://purl.uniprot.org/core/author"Hoeh P."xsd:string
http://purl.uniprot.org/citations/8319294http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8319294http://purl.uniprot.org/core/name"Curr Genet"xsd:string
http://purl.uniprot.org/citations/8319294http://purl.uniprot.org/core/pages"392-396"xsd:string
http://purl.uniprot.org/citations/8319294http://purl.uniprot.org/core/title"Phenotypic identification of amplifications of the ADH4 and CUP1 genes of Saccharomyces cerevisiae."xsd:string
http://purl.uniprot.org/citations/8319294http://purl.uniprot.org/core/volume"23"xsd:string
http://purl.uniprot.org/citations/8319294http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8319294
http://purl.uniprot.org/citations/8319294http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8319294
http://purl.uniprot.org/uniprot/#_P0CX80-mappedCitation-8319294http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8319294
http://purl.uniprot.org/uniprot/#_P0CX81-mappedCitation-8319294http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8319294
http://purl.uniprot.org/uniprot/#_P10127-mappedCitation-8319294http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8319294
http://purl.uniprot.org/uniprot/P10127http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/8319294
http://purl.uniprot.org/uniprot/P0CX80http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/8319294
http://purl.uniprot.org/uniprot/P0CX81http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/8319294