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http://purl.uniprot.org/citations/8323553http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8323553http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8323553http://www.w3.org/2000/01/rdf-schema#comment"c-Rmil is the cellular allele of the v-Rmil oncogene, transduced during in vitro passaging of Rous associated virus type 1 in chicken embryonic neuroretina (NR) cells. The c-Rmil proto-oncogene is the avian homolog of the mammalian B-raf gene and belongs to the mil/raf oncogene family of serine/threonine protein kinases. We recently reported that the avian c-Rmil gene encodes two proteins of 94 and 95 kDa, resulting from an alternative splicing mechanism. We describe here the exon-intron organization of the coding region of the chicken c-Rmil locus. We show that c-Rmil proteins are encoded by 19 exons lying within about 100 kbp of genomic DNA. Comparison of the organization of this gene with those of the other mil/raf genes shows strong similarities within three conserved domains previously identified in mil/raf protein kinases. However, c-Rmil contains two additional 5' coding exons that are not present in the other mil/raf genes."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1993.1770"xsd:string
http://purl.uniprot.org/citations/8323553http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1993.1770"xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Marx M."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Marx M."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Barnier J.V."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Barnier J.V."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Calogeraki I."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Calogeraki I."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Calothy G."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Calothy G."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Eychene A."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Eychene A."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Felder M.-P."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/author"Felder M.-P."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/pages"1324-1331"xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/pages"1324-1331"xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/title"Genomic organization and nucleotide sequence of the coding region of the chicken c-Rmil(B-raf-1) proto-oncogene."xsd:string
http://purl.uniprot.org/citations/8323553http://purl.uniprot.org/core/title"Genomic organization and nucleotide sequence of the coding region of the chicken c-Rmil(B-raf-1) proto-oncogene."xsd:string