http://purl.uniprot.org/citations/8381386 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8381386 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8381386 | http://www.w3.org/2000/01/rdf-schema#comment | "The murine retinoid X receptor beta (mRXR beta) is a nuclear hormone receptor that activates transcription of murine major histocompatibility complex (MHC) class I genes in response to retinoic acid. In this study, the human RXR beta gene was mapped onto the short arm or centromeric region of chromosome 6 (6pter-q13), which also harbors the MHC. Chromosomal localization was performed by Southern hybridization of genomic DNA from human rodent cell hybrids with the mRXR beta gene as a probe. In addition, a full-length cDNA clone encoding a human RXR beta was isolated by nucleic acid screening of a human cDNA library with a fragment of the mRXR beta gene as a probe. Comparison of the nucleotide-coding sequences of the human and the murine RXR beta revealed a predominance of third base substitutions, resulting in selective conservation of the predicted amino acid sequence of the proteins. The overall sequence homology was 97.6% on the amino acid level as opposed to 91.6% on the nucleotide level. In Northern hybridization experiments with the human cDNA as a probe, RXR beta gene transcripts were detected in a variety of human tumor cell lines, regardless of whether these cell lines expressed MHC class I genes."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf00217449"xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf00217449"xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/author | "McBride O.W."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/author | "McBride O.W."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/author | "Ozato K."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/author | "Ozato K."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/author | "Yang S.Y."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/author | "Yang S.Y."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/author | "DiSanto J.P."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/author | "DiSanto J.P."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/author | "Fleischhauer K."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/author | "Fleischhauer K."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/name | "Hum. Genet."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/name | "Hum. Genet."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/pages | "505-510"xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/pages | "505-510"xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/title | "Cloning and chromosome mapping of human retinoid X receptor beta: selective amino acid sequence conservation of a nuclear hormone receptor in mammals."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/title | "Cloning and chromosome mapping of human retinoid X receptor beta: selective amino acid sequence conservation of a nuclear hormone receptor in mammals."xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/volume | "90"xsd:string |
http://purl.uniprot.org/citations/8381386 | http://purl.uniprot.org/core/volume | "90"xsd:string |