http://purl.uniprot.org/citations/8391931 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8391931 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8391931 | http://www.w3.org/2000/01/rdf-schema#comment | "CD30 is a surface marker for neoplastic cells of Hodgkin's lymphoma and shows sequence homology to members of the tumor necrosis factor (TNF) receptor superfamily. Using a chimeric probe consisting of the extracellular domain of CD30 fused to truncated immunoglobulin heavy chains, we expression cloned the cDNA cognate from the murine T cell clone 7B9. The encoded protein is a 239 amino acid type II membrane protein whose C-terminal domain shows significant homology to TNF alpha, TNF beta, and the CD40L. Cross-hybridization to an induced peripheral blood T cell cDNA library yielded the human homolog, which is 72% identical at the amino acid level. The recombinant human ligand enhances the proliferation of CD3-activated T cells yet induces differential responses, including cell death, in several CD30+ lymphoma-derived clones. The human and murine genes map to 9q33 and the proximal region of chromosome 4, respectively."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(93)90361-s"xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(93)90361-s"xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Anderson D."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Anderson D."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Armitage R.J."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Armitage R.J."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Farrah T."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Farrah T."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Copeland N.G."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Copeland N.G."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Jenkins N.A."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Jenkins N.A."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Smith C.A."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Smith C.A."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Baker E."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Baker E."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Sutherland G.R."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Sutherland G.R."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Davis T."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Davis T."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Goodwin R.G."xsd:string |
http://purl.uniprot.org/citations/8391931 | http://purl.uniprot.org/core/author | "Goodwin R.G."xsd:string |