| http://purl.uniprot.org/citations/8396206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8396206 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8396206 | http://www.w3.org/2000/01/rdf-schema#comment | "Schistosomes switch rapidly from the use of stored glycogen to a reliance on host glucose during the transformation from free-living cercariae to parasitic schistosomula. We have cloned a set of cDNAs encoding proteins involved in glucose metabolism to allow us to examine the expression of these genes during this transformation. We first obtained and characterized Schistosoma mansoni cDNA clones encoding the tricarboxylic acid cycle enzyme, mitochondrial malate dehydrogenase (SMDH) and the mitochondrial encoded electron transport protein, cytochrome oxidase subunit 1 (SCOX1). Northern blots were then prepared using mRNA isolated from whole cercariae, cercarial tails, schistosomula, adult males and adult females. The Northern blots were successively hybridized with a variety of probes including those for SMDH, SCOX, the glycolytic enzymes, hexokinase, triosephosphate isomerase and glyceraldehyde-3-phosphate dehydrogenase and several control probes. Probes were additionally hybridized to mRNA dot blots and the signals were quantified using storage phosphor technology. These studies reveal that transcripts encoding these metabolic enzymes are localized at much higher levels in cercarial tails than in whole cercariae or transformed schistosomula, and support the notion of a dominant aerobic metabolism in tails. Male and female adult worms express each of the mRNAs at roughly equal levels. Adults express the metabolic mRNAs, including those involved in oxidative glucose metabolism, at relatively high levels suggesting that adult schistosomes retain a significant capacity to produce energy through aerobic metabolism."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.org/dc/terms/identifier | "doi:10.1016/0166-6851(93)90032-s"xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.org/dc/terms/identifier | "doi:10.1016/0166-6851(93)90032-s"xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.org/dc/terms/identifier | "doi:10.1016/0166-6851(93)90032-S"xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/author | "Stein L.D."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/author | "Stein L.D."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/author | "Shoemaker C.B."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/author | "Shoemaker C.B."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/author | "Skelly P.J."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/author | "Skelly P.J."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/name | "Mol. Biochem. Parasitol."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/name | "Mol. Biochem. Parasitol."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/pages | "93-104"xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/pages | "93-104"xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/title | "Expression of Schistosoma mansoni genes involved in anaerobic and oxidative glucose metabolism during the cercaria to adult transformation."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/title | "Expression of Schistosoma mansoni genes involved in anaerobic and oxidative glucose metabolism during the cercaria to adult transformation."xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/volume | "60"xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://purl.uniprot.org/core/volume | "60"xsd:string |
| http://purl.uniprot.org/citations/8396206 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8396206 |
| http://purl.uniprot.org/citations/8396206 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8396206 |
| http://purl.uniprot.org/citations/8396206 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8396206 |