http://purl.uniprot.org/citations/8402894 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8402894 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8402894 | http://www.w3.org/2000/01/rdf-schema#comment | "Bacteriophage T4 Alc protein participates in shutting off host transcription after infection of E. coli. It is demonstrated that Alc acts as a site-specific termination factor. The Alc sites occur frequently in E. coli DNA, resulting in early cessation of elongation in several tested transcription units. Alc-dependent termination requires unimpeded propagation of the elongating complex as it approaches the Alc site. Temporary halting of RNA polymerase within 10-15 bp before the Alc site prevents termination. Bacteriophage T4 transcription is protected from the action of Alc by overall substitution of cytosine with 5-hydroxymethyl cytosine in T4 DNA. In vitro methylation of CpG sequences in the vicinity of an Alc site abolishes the effect of Alc. Thus, Alc-dependent termination involves local sensing of the state of cytosine modification and a short-term "memory" of recent pausing."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(05)80091-1"xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(05)80091-1"xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/author | "Kutter E."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/author | "Kutter E."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/author | "Goldfarb A."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/author | "Goldfarb A."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/author | "Kashlev M."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/author | "Kashlev M."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/author | "Nudler E."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/author | "Nudler E."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/author | "White T."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/author | "White T."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/pages | "147-154"xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/pages | "147-154"xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/title | "Bacteriophage T4 Alc protein: a transcription termination factor sensing local modification of DNA."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/title | "Bacteriophage T4 Alc protein: a transcription termination factor sensing local modification of DNA."xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/volume | "75"xsd:string |
http://purl.uniprot.org/citations/8402894 | http://purl.uniprot.org/core/volume | "75"xsd:string |