| http://purl.uniprot.org/citations/8413235 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8413235 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8413235 | http://www.w3.org/2000/01/rdf-schema#comment | "The tsBN7 cell line, one of the mutant lines temperature sensitive for growth which have been isolated from the BHK21 cell line, was found to die by apoptosis following a shift to the nonpermissive temperature. The induced apoptosis was inhibited by a protein synthesis inhibitor, cycloheximide, but not by the bcl-2-encoded protein. By DNA-mediated gene transfer, we cloned a cDNA that complements the tsBN7 mutation. It encodes a novel hydrophobic protein, designated DAD1, which is well conserved (100% identical amino acids between humans and hamsters). By comparing the base sequences of the parental BHK21 and tsBN7 DAD1 cDNAs, we found that the DAD1-encoding gene is mutated in tsBN7 cells. The DAD1 protein disappeared in tsBN7 cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggers apoptosis."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.13.10.6367-6374.1993"xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.13.10.6367-6374.1993"xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Fukushima K."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Fukushima K."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Shibata Y."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Shibata Y."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Nishimoto T."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Nishimoto T."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Nakashima T."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Nakashima T."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Sekiguchi T."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Sekiguchi T."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Komiyama S."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Komiyama S."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Kuraoka A."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/author | "Kuraoka A."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/pages | "6367-6374"xsd:string |
| http://purl.uniprot.org/citations/8413235 | http://purl.uniprot.org/core/pages | "6367-6374"xsd:string |