| http://purl.uniprot.org/citations/8415706 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8415706 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8415706 | http://www.w3.org/2000/01/rdf-schema#comment | "We report the molecular cloning and characterization of two structurally related putative receptor tyrosine kinases, encoded by distinct genes (tie-1 and tie-2) on mouse chromosome 4. Both tie-1 and tie-2 encode receptor proteins possessing unique multiple extracellular domains: two immunoglobulin-like loop domains flanking three epidermal growth factor repeats followed by three fibronectin-type III repeats. Both genes are expressed in early embryonic vascular system and in maternal decidual vascular endothelial cells, where the vasculature undergoes an active angiogenesis. tie-2, but not tie-1, expression was also detected in extraembryonic mesoderm of the amnion. tie-1, but not tie-2, is expressed in an acute myelogenic cell line in vitro. tie-1 and tie-2 may form another class within the receptor tyrosine kinase gene family, and further characterization of these genes and identification of their putative ligands should define the nature of the signal-transduction cascades underlying early vascular system development, as well as their differential roles in mesodermal cells of the amniotic and myeloid lineages."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.90.20.9355"xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.90.20.9355"xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/author | "Kozak C.A."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/author | "Kozak C.A."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/author | "Qin Y."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/author | "Qin Y."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/author | "Sato T.N."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/author | "Sato T.N."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/author | "Andus K.L."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/author | "Andus K.L."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/pages | "9355-9358"xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/pages | "9355-9358"xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/title | "Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/title | "Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system."xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/volume | "90"xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://purl.uniprot.org/core/volume | "90"xsd:string |
| http://purl.uniprot.org/citations/8415706 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8415706 |
| http://purl.uniprot.org/citations/8415706 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8415706 |