http://purl.uniprot.org/citations/8421313 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8421313 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8421313 | http://www.w3.org/2000/01/rdf-schema#comment | "A family of toxic proteins, the isoabrins, which possess N-glycosylase activity toward eukaryotic 28 S r-RNA, may have potential use in cancer chemotherapy. By polymerase chain reaction techniques, cDNA clones of three isoabrins, carrying A and B-chain sequences, were isolated and their nucleotide sequences were determined. The isoabrins consist of an A-chain comprised of 250 of 251 amino acids, followed by a 10 amino acid linker and a B-chain of 267 amino acids. There is substantial conservation in the B-chain of the three isoabrins, with less than six amino acid substitutions, whereas as many as 46 amino acid substitutions occur in the A-chains. Based on the relationships between the biological activities and the putative amino acid sequences of the isoabrins, three isoabrins, abrin-a, -b and -d, could be identified and the potential epitope of immunological response of these isoabrins could be assigned."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.org/dc/terms/identifier | "doi:10.1006/jmbi.1993.1029"xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.org/dc/terms/identifier | "doi:10.1006/jmbi.1993.1029"xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/author | "Lee M.-C."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/author | "Lee M.-C."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/author | "Hung C.-H."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/author | "Hung C.-H."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/author | "Lee T.-C."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/author | "Lee T.-C."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/author | "Lin J.-Y."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/author | "Lin J.-Y."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/name | "J. Mol. Biol."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/name | "J. Mol. Biol."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/pages | "263-267"xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/pages | "263-267"xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/title | "Primary structure of three distinct isoabrins determined by cDNA sequencing. Conservation and significance."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/title | "Primary structure of three distinct isoabrins determined by cDNA sequencing. Conservation and significance."xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/volume | "229"xsd:string |
http://purl.uniprot.org/citations/8421313 | http://purl.uniprot.org/core/volume | "229"xsd:string |
http://purl.uniprot.org/citations/8421313 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8421313 |
http://purl.uniprot.org/citations/8421313 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8421313 |