http://purl.uniprot.org/citations/8423781 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8423781 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8423781 | http://www.w3.org/2000/01/rdf-schema#comment | "A tandemly arranged multigene family encoding putative hexose transporters in Trypanosoma brucei has been characterized. It is composed of two 80% homologous groups of genes called THT1 (six copies) and THT2 (five copies). When Xenopus oocytes are microinjected with in vitro-transcribed RNA from a THT1 gene, they express a glucose transporter with properties similar to those of the trypanosome bloodstream-form protein(s). This THT1-encoded transport system for glucose differs from the human erythrocyte-type glucose transporter by its moderate sensitivity to cytochalasin B and its capacity to transport D-fructose. These properties suggest that the trypanosomal transporter may be a good target for antitrypanosomal drugs. mRNA analysis revealed that expression of these genes was life cycle stage dependent. Bloodstream forms express 40-fold more THT1 than THT2. In contrast, procyclic trypanosomes express no detectable THT1 but demonstrate glucose-dependent expression of THT2."xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.13.2.1146-1154.1993"xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.13.2.1146-1154.1993"xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/author | "Bringaud F."xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/author | "Bringaud F."xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/author | "Baltz T."xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/author | "Baltz T."xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/pages | "1146-1154"xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/pages | "1146-1154"xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/title | "Differential regulation of two distinct families of glucose transporter genes in Trypanosoma brucei."xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/title | "Differential regulation of two distinct families of glucose transporter genes in Trypanosoma brucei."xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/volume | "13"xsd:string |
http://purl.uniprot.org/citations/8423781 | http://purl.uniprot.org/core/volume | "13"xsd:string |
http://purl.uniprot.org/citations/8423781 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8423781 |
http://purl.uniprot.org/citations/8423781 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8423781 |
http://purl.uniprot.org/citations/8423781 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8423781 |
http://purl.uniprot.org/citations/8423781 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8423781 |
http://purl.uniprot.org/uniprot/Q09037 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/8423781 |
http://purl.uniprot.org/uniprot/Q06222 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/8423781 |