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http://purl.uniprot.org/citations/8459767http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8459767http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8459767http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8459767http://www.w3.org/2000/01/rdf-schema#comment"Mycobacteriophage L5 is a temperate phage of the mycobacteria that forms stable lysogens in Mycobacterium smegmatis. We show here that the 183-amino-acid product of L5 gene 71 confers immunity to L5 superinfection, is required for maintenance of the lysogenic state and contains a helix-turn-helix DNA-binding motif--properties associated with repressors of temperate phages. We have utilized these observations to demonstrate the use of L5 gene 71 as a selectable marker for genetic transformation of the mycobacteria. Significantly, the use of L5 gene 71 as a selectable gene avoids the requirement for antibiotic-resistance genes providing an important tool for manipulation of the pathogens Mycobacterium tuberculosis and Mycobacterium avium, and for the construction of recombinant BCG vaccines."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.org/dc/terms/identifier"doi:10.1111/j.1365-2958.1993.tb01132.x"xsd:string
http://purl.uniprot.org/citations/8459767http://purl.org/dc/terms/identifier"doi:10.1111/j.1365-2958.1993.tb01132.x"xsd:string
http://purl.uniprot.org/citations/8459767http://purl.org/dc/terms/identifier"doi:10.1111/j.1365-2958.1993.tb01132.x"xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/author"Hatfull G.F."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/author"Hatfull G.F."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/author"Hatfull G.F."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/author"Jacobs W.R. Jr."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/author"Jacobs W.R. Jr."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/author"Jacobs W.R."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/author"Jacobs W.R."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/author"Donnelly-Wu M.K."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/author"Donnelly-Wu M.K."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/author"Donnelly-Wu M.K."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/name"Mol. Microbiol."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/name"Mol. Microbiol."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/name"Mol. Microbiol."xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/pages"407-417"xsd:string
http://purl.uniprot.org/citations/8459767http://purl.uniprot.org/core/pages"407-417"xsd:string