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| http://purl.uniprot.org/citations/8464923 | http://www.w3.org/2000/01/rdf-schema#comment | "Receptors for the major excitatory neurotransmitter glutamate may play key roles in neurodegeneration. The mouse Glur-5 gene maps to chromosome 16 between App and Sod-1. The homologous human GLUR5 gene maps to the corresponding region of human chromosome 21, which contains the locus for familial amyotrophic lateral sclerosis. This location, and other features, render GLUR5 a possible candidate gene for familial amyotrophic lateral sclerosis. In addition, dosage imbalance of GLUR5 may have a role in the trisomy 21 (Down syndrome). Further characterization of the murine glutamate receptor family includes mapping of Glur-1 to the same region as neurological mutants spasmodic, shaker-2, tipsy, and vibrator on chromosome 11; Glur-2 near spastic on chromosome 3; Glur-6 near waltzer and Jackson circler on chromosome 10; and Glur-7 near clasper on chromosome 4."xsd:string |
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| http://purl.uniprot.org/citations/8464923 | http://purl.uniprot.org/core/author | "Haines J.L."xsd:string |
| http://purl.uniprot.org/citations/8464923 | http://purl.uniprot.org/core/author | "Rochelle J.M."xsd:string |
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| http://purl.uniprot.org/citations/8464923 | http://purl.uniprot.org/core/author | "Dackowski W."xsd:string |
| http://purl.uniprot.org/citations/8464923 | http://purl.uniprot.org/core/author | "Uhl G.R."xsd:string |
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| http://purl.uniprot.org/citations/8464923 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
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| http://purl.uniprot.org/citations/8464923 | http://purl.uniprot.org/core/title | "Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans."xsd:string |
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