| http://purl.uniprot.org/citations/8471022 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8471022 | http://www.w3.org/2000/01/rdf-schema#comment | "The peptidase system in Drosophila melanogaster (dipeptidase-A, -B, and -C and leucine aminopeptidases G and P) was used as a model to study the effects of modifier genes on activity of enzymes with similar functions. A screen of X, second, and third chromosome substitution isogenic lines revealed the presence of activity modifiers for peptidases on all three chromosomes. Correlation analyses indicated that covariation between some of the peptidase activities is independent of genetic background, while others are associated with variable second chromosomes. Chromosome-specific effects on Km, Vmax, and specific activity of partially purified peptidases were also detected. Moreover, a repeatable technique using anion-exchange column chromatography allowed the characterization of possibly two putative peptidic enzymes, glycyl-L-isoleucine-ase and L-leucyl-L-proline-ase, whose kinetic properties differ from the dipeptidases and the leucine aminopeptidases. These findings confirm the existence of activity modifiers for peptidases, much like other enzymes in Drosophila melanogaster."xsd:string |
| http://purl.uniprot.org/citations/8471022 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf02399818"xsd:string |
| http://purl.uniprot.org/citations/8471022 | http://purl.uniprot.org/core/author | "Hiraizumi K."xsd:string |
| http://purl.uniprot.org/citations/8471022 | http://purl.uniprot.org/core/author | "Mathes K.D."xsd:string |
| http://purl.uniprot.org/citations/8471022 | http://purl.uniprot.org/core/author | "Shalish C.I."xsd:string |
| http://purl.uniprot.org/citations/8471022 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8471022 | http://purl.uniprot.org/core/name | "Biochem Genet"xsd:string |
| http://purl.uniprot.org/citations/8471022 | http://purl.uniprot.org/core/pages | "29-50"xsd:string |
| http://purl.uniprot.org/citations/8471022 | http://purl.uniprot.org/core/title | "Chromosomal effects on peptidase activities in Drosophila melanogaster."xsd:string |
| http://purl.uniprot.org/citations/8471022 | http://purl.uniprot.org/core/volume | "31"xsd:string |
| http://purl.uniprot.org/citations/8471022 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8471022 |
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