http://purl.uniprot.org/citations/8489740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8489740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8489740 | http://www.w3.org/2000/01/rdf-schema#comment | "Using an extraction procedure that minimized proteolysis, followed by gel filtration, cation-exchange FPLC, and reverse-phase HPLC, the present study unambiguously showed the presence of multiple isoforms of relaxin in the ovaries of pregnant sows. Four relaxin isoforms were isolated (designated as R-I1, R-I2, R-II1 and R-III1). They had a similar migration pattern on SDS/urea PAGE, and showed no significant difference in biological activity. HPLC separation of the reduced and S-pyridylethylated relaxin variants indicated that R-I1, R-I2 and R-III1 each contained multiple relaxin molecules which showed variability of the B-chain, whereas R-II1 contained mostly a single relaxin molecule with only slight B-chain variability. R-II1 was thus considered likely to be the major form of relaxin stored in the ovary. Sequence analysis revealed that R-II1 contained 22 amino-acid residues in the A-chain and 29 residues in the B-chain, with a total molecular mass of 5814.8 Da. It was thus equivalent to CM-a' relaxin designated by Sherwood and O'Byrne (1974)."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.org/dc/terms/identifier | "doi:10.1515/bchm3.1993.374.1-6.203"xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/author | "Sugawara K."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/author | "Sugawara K."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/author | "Takahara H."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/author | "Takahara H."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/author | "Tagami S."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/author | "Tagami S."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/author | "Kohsaka T."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/author | "Kohsaka T."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/name | "Biol. Chem. Hoppe-Seyler"xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/name | "Biol Chem Hoppe Seyler"xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/pages | "203-210"xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/pages | "203-210"xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/title | "Endogenous heterogeneity of relaxin and sequence of the major form in pregnant sow ovaries."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/title | "Endogenous heterogeneity of relaxin and sequence of the major form in pregnant sow ovaries."xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/volume | "374"xsd:string |
http://purl.uniprot.org/citations/8489740 | http://purl.uniprot.org/core/volume | "374"xsd:string |
http://purl.uniprot.org/citations/8489740 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8489740 |
http://purl.uniprot.org/citations/8489740 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8489740 |
http://purl.uniprot.org/citations/8489740 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8489740 |