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| http://purl.uniprot.org/citations/8514138 | http://www.w3.org/2000/01/rdf-schema#comment | "We have identified of set of related transcripts expressed in the germ line of male Drosophila melanogaster. Surprisingly, while one of the corresponding genes is autosomal the remainder are located on the Y chromosome. The autosomal locus, at 77F on chromosome arm 3L, corresponds to the previously described transcription unit 18c, located in the first intron of the gene for an RI subunit of cAMP-dependent protein kinase. The Y chromosome copies have been mapped to region h18-h19 on the cytogenetic map of the Y outside of any of the regions required for male fertility. In contrast to D. melanogaster, where Y-linked copies were found in nine different wild-type strains, no Y-linked copies were found in sibling species. Several apparently Y-derived cDNA clones and one Y-linked genomic clone have been sequenced. The Y-derived genomic DNA shares the same intron/exon structure as the autosomal copy as well as related flanking sequences suggesting that it transposed to the Y from the autosomal locus. However, this particular Y-linked copy cannot encode a functional polypeptide due to a stop codon at amino acid position 72. Divergence among five different cDNA clones ranges from 1.5 to 6% and includes a large number of third position substitutions. We have not yet obtained a full-length cDNA from a Y-linked gene and therefore cannot conclude that the D. melanogaster Y chromosome contains functional protein-coding genes. The autosomal gene encodes a predicted polypeptide with 45% similarity to histones of the H5 class and more limited similarity to cysteine-rich protamines. This protein may be a distant relative of the histone H1 family perhaps involved in sperm chromatin condensation."xsd:string |
| http://purl.uniprot.org/citations/8514138 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/134.1.293"xsd:string |
| http://purl.uniprot.org/citations/8514138 | http://purl.uniprot.org/core/author | "Kaiser K."xsd:string |
| http://purl.uniprot.org/citations/8514138 | http://purl.uniprot.org/core/author | "Russell S.R."xsd:string |
| http://purl.uniprot.org/citations/8514138 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8514138 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/8514138 | http://purl.uniprot.org/core/pages | "293-308"xsd:string |
| http://purl.uniprot.org/citations/8514138 | http://purl.uniprot.org/core/title | "Drosophila melanogaster male germ line-specific transcripts with autosomal and Y-linked genes."xsd:string |
| http://purl.uniprot.org/citations/8514138 | http://purl.uniprot.org/core/volume | "134"xsd:string |
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