http://purl.uniprot.org/citations/8521472 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8521472 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8521472 | http://www.w3.org/2000/01/rdf-schema#comment | "We have identified a novel 100 kDa coiled-coil protein, rabaptin-5, that specifically interacts with the GTP form of the small GTPase Rab5, a potent regulator of endocytic transport. It is mainly cytosolic, but a fraction colocalizes with Rab5 to early endosomes. Expression of a GTPase-deficient Rab5 mutant enhances the binding of rabaptin-5 to enlarged endosomes. Overexpression of rabaptin-5 alone is sufficient to promote expansion of early endosomes. Rab5 recruits rabaptin-5 to purified early endosomes in a GTP-dependent manner, demonstrating functional similarities with other members of the Ras superfamily. Immunodepletion of rabaptin-5 from cytosol strongly inhibits Rab5-dependent early endosome fusion. Rabaptin-5 is thus a Rab effector required for membrane docking and fusion."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(95)90120-5"xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(95)90120-5"xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/author | "Stenmark H."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/author | "Stenmark H."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/author | "Zerial M."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/author | "Zerial M."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/author | "Vitale G."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/author | "Vitale G."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/author | "Ulrich O."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/author | "Ulrich O."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/pages | "423-432"xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/pages | "423-432"xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/title | "Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/title | "Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion."xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/volume | "83"xsd:string |
http://purl.uniprot.org/citations/8521472 | http://purl.uniprot.org/core/volume | "83"xsd:string |
http://purl.uniprot.org/citations/8521472 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8521472 |
http://purl.uniprot.org/citations/8521472 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8521472 |