| http://purl.uniprot.org/citations/8524242 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8524242 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8524242 | http://www.w3.org/2000/01/rdf-schema#comment | "The poly(A)-binding protein (PABP) binds to the poly(A) tail present at the 3' ends of most eukaryotic mRNAs. PABP is thought to play a role in both translation and mRNA stability. Here we describe the molecular cloning and characterization of an inducible PABP, iPABP, from a cDNA library prepared from activated T cells. iPABP shows 79% sequence identity to PABP at the amino acid level. The RNA binding domains of iPABP and PABP are nearly identical, while their C termini are more divergent. Like PABP, iPABP is primarily localized to the cytoplasm. iPABP is expressed at low levels in resting normal human T cells; following T-cell activation, however, iPABP mRNA levels are rapidly up-regulated. In contrast, PABP is constitutively expressed in both resting and activated T cells. iPABP mRNA was also expressed at much higher levels than PABP mRNA in heart and skeletal muscle tissue. These data suggest that the regulation of cytoplasmic poly(A)-binding activity is more complex than previously believed. In most tissues, poly(A)-binding activity is likely to be the result of the combined effects of constitutively expressed PABP and iPABP, whose expression is subject to more complex regulation."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.15.12.6770"xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.15.12.6770"xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/author | "Yang H."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/author | "Yang H."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/author | "Lindsten T."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/author | "Lindsten T."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/author | "Duckett C.S."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/author | "Duckett C.S."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/pages | "6770-6776"xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/pages | "6770-6776"xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/title | "iPABP, an inducible poly(A)-binding protein detected in activated human T cells."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/title | "iPABP, an inducible poly(A)-binding protein detected in activated human T cells."xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/volume | "15"xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://purl.uniprot.org/core/volume | "15"xsd:string |
| http://purl.uniprot.org/citations/8524242 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8524242 |
| http://purl.uniprot.org/citations/8524242 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8524242 |
| http://purl.uniprot.org/citations/8524242 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8524242 |
| http://purl.uniprot.org/citations/8524242 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8524242 |