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| http://purl.uniprot.org/citations/8524796 | http://www.w3.org/2000/01/rdf-schema#comment | "We have identified an amino acid sequence in the Drosophila Transformer (Tra) protein that is capable of directing a heterologous protein to nuclear speckles, regions of the nucleus previously shown to contain high concentrations of spliceosomal small nuclear RNAs and splicing factors. This sequence contains a nucleoplasmin-like bipartite nuclear localization signal (NLS) and a repeating arginine/serine (RS) dipeptide sequence adjacent to a short stretch of basic amino acids. Sequence comparisons from a number of other splicing factors that colocalize to nuclear speckles reveal the presence of one or more copies of this motif. We propose a two-step subnuclear localization mechanism for splicing factors. The first step is transport across the nuclear envelope via the nucleoplasmin-like NLS, while the second step is association with components in the speckled domain via the RS dipeptide sequence."xsd:string |
| http://purl.uniprot.org/citations/8524796 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.92.25.11524"xsd:string |
| http://purl.uniprot.org/citations/8524796 | http://purl.uniprot.org/core/author | "Maniatis T."xsd:string |
| http://purl.uniprot.org/citations/8524796 | http://purl.uniprot.org/core/author | "Amrein H."xsd:string |
| http://purl.uniprot.org/citations/8524796 | http://purl.uniprot.org/core/author | "Hedley M.L."xsd:string |
| http://purl.uniprot.org/citations/8524796 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/8524796 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/8524796 | http://purl.uniprot.org/core/pages | "11524-11528"xsd:string |
| http://purl.uniprot.org/citations/8524796 | http://purl.uniprot.org/core/title | "An amino acid sequence motif sufficient for subnuclear localization of an arginine/serine-rich splicing factor."xsd:string |
| http://purl.uniprot.org/citations/8524796 | http://purl.uniprot.org/core/volume | "92"xsd:string |
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