| http://purl.uniprot.org/citations/8537381 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8537381 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8537381 | http://www.w3.org/2000/01/rdf-schema#comment | "We have cloned a novel member of the CLC chloride channel family from rat brain, rCLC-5. The cDNA predicts a 83-kDa protein belonging to the branch including CLC-3 and CLC-4, with which it shares approximately 80% identity. Expression of rCLC-5 in Xenopus oocytes elicits novel anion currents. They are strongly outwardly rectifying and have a conductivity sequence of NO3- > Cl- > Br- > I->> glutamate-. Although CLC-5 has consensus sites for phosphorylation by protein kinase A, raising the intracellular cAMP concentration had no effect on these currents. Currents were also unchanged when rCLC-5 was coexpressed with rCLC-3 and rCLC-4, either singly or in combination. rCLC-5 is expressed predominantly in kidney and also in brain, lung, and liver. Along the nephron, rCLC-5 message is detectable in all tubule segments investigated, but expression in the glomerulus and the S2 segment of the proximal tubule is low."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.52.31172"xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.52.31172"xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/author | "Jentsch T.J."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/author | "Jentsch T.J."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/author | "Bens M."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/author | "Bens M."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/author | "Schwappach B."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/author | "Schwappach B."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/author | "Steinmeyer K."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/author | "Steinmeyer K."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/author | "Vandewalle A."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/author | "Vandewalle A."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/pages | "31172-31177"xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/pages | "31172-31177"xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/title | "Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/title | "Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease."xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/volume | "270"xsd:string |
| http://purl.uniprot.org/citations/8537381 | http://purl.uniprot.org/core/volume | "270"xsd:string |