| http://purl.uniprot.org/citations/8599092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8599092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8599092 | http://www.w3.org/2000/01/rdf-schema#comment | "The pleiotropic biological activities of interleukin-1 (IL-1) are mediated by its type I receptor (IL-1RI). When the ligand binds, IL-1RI initiates a signaling cascade that results in the activation of the transcription regulator nuclear factor kappa B (NF-kappa B). A protein kinase designated IRAK (IL-1 receptor-associated kinase) was purified, and its complementary DNA was molecularly cloned. When human embryonic kidney cells (cell line 293) over-expressing IL-1RI or HeLa cells were exposed to IL-1, IRAK rapidly associated with the IL-1RI complex and was phosphorylated. The primary amino acid sequence of IRAK shares similarity with that of Pelle, a protein kinase that is essential for the activation of a NF-kappa B homolog in Drosophila."xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.271.5252.1128"xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.271.5252.1128"xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/author | "Cao Z."xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/author | "Cao Z."xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/author | "Gao X."xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/author | "Gao X."xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/author | "Henzel W.J."xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/author | "Henzel W.J."xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/pages | "1128-1131"xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/pages | "1128-1131"xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/title | "IRAK: a kinase associated with the interleukin-1 receptor."xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/title | "IRAK: a kinase associated with the interleukin-1 receptor."xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/volume | "271"xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://purl.uniprot.org/core/volume | "271"xsd:string |
| http://purl.uniprot.org/citations/8599092 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8599092 |
| http://purl.uniprot.org/citations/8599092 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8599092 |
| http://purl.uniprot.org/citations/8599092 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8599092 |
| http://purl.uniprot.org/citations/8599092 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8599092 |