| http://purl.uniprot.org/citations/8602848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8602848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8602848 | http://www.w3.org/2000/01/rdf-schema#comment | "The gene encoding a putative mouse bradykinin B1 receptor was cloned from a genomic library by low stringency screening. Analysis of two isolated clones revealed a region which contains an open reading frame uninterrupted by introns and encodes a 334 amino acid protein, which exhibits seven potential transmembrane domains and is 68% identical to the human and rabbit bradykinin B1 receptors. Lipopolysaccharide-treatment induces B1 receptor transcripts in the heart, liver, and lung. Stable expression of the coding region in COS-7 cells resulted in high levels of binding sites for the specific B1 ligand des-ARG10 kallidin (Kd = 1.3 nM; Bmax = 51 fmol/mg protein). The rank order of affinity of the receptor for the agonists and antagonists was: des-Arg9BKdes-Arg9Leu8BKdes-Arg10kallidin >> Hoe-140=bradykinin. Functional coupling of the cloned receptor was demonstrated by the dose-dependent effects of des-Arg(9)BK on the extracellular acidification rate in stably transfected COS-7 cells. This effect was not produced by bradykinin and could be blocked by the B1 antagonist des-Arg9Leu8BK."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1996.0384"xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1996.0384"xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Ganten D."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Ganten D."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Pesquero J.B."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Pesquero J.B."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Roscher A.A."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Roscher A.A."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Bader M."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Bader M."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Metzger R."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Metzger R."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Oliveira S.M."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Oliveira S.M."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Pesquero J.L."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/author | "Pesquero J.L."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/pages | "219-225"xsd:string |
| http://purl.uniprot.org/citations/8602848 | http://purl.uniprot.org/core/pages | "219-225"xsd:string |