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http://purl.uniprot.org/citations/8605245http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8605245http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8605245http://www.w3.org/2000/01/rdf-schema#comment"A member of the ras gene superfamily, belonging to the rap family and designated Pprap1, was isolated from a cDNA library from the true slime mold Physarum polycephalum by plaque hybridization in combination with 5'-RACE. The assembled nucleotide sequence of Pprap1 (1062 bp) has an open reading frame coding for a protein of 188 amino acids of a calculated M(r) of 21035. This protein exhibits: (i) a highly conserved GTP binding domain containing a putative effector domain, with the threonine-for-glutamine substitution characteristic of rap proteins, (ii) a hypervariable domain, and (iii) the CAAX motif. Analysis of the C-terminal amino acid sequence of Pprap1 shows that it presumably undergoes geranylgeranylation but is not palmitoylated; however, it contains a lysine-rich domain which might serve as the second membrane localization signal. Pprap1 exhibits significantly high amino acid homology within the GTP binding domain with its homologues: Ddrap1 from Dictyostelium discoideum (92%) and human Rap1A (83%), and relatively low homology (59%) with the Saccharomyces cerevisiae homologue, RSR1. It has also 59% and 61% homology with the P. polycephalum Ppras1 and Ppras2 proteins, respectively. This gene is the third member of the ras gene superfamily identified in P. polycephalum so far."xsd:string
http://purl.uniprot.org/citations/8605245http://purl.org/dc/terms/identifier"doi:10.1016/0167-4781(95)00207-3"xsd:string
http://purl.uniprot.org/citations/8605245http://purl.org/dc/terms/identifier"doi:10.1016/0167-4781(95)00207-3"xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/author"Kozlowski P."xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/author"Kozlowski P."xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/author"Toczko K."xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/author"Toczko K."xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/author"Trzcinska-Danielewicz J."xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/author"Trzcinska-Danielewicz J."xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/name"Biochim. Biophys. Acta"xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/name"Biochim. Biophys. Acta"xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/pages"29-33"xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/pages"29-33"xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/title"Identification and sequence analysis of a rap gene from the true slime mold Physarum polycephalum."xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/title"Identification and sequence analysis of a rap gene from the true slime mold Physarum polycephalum."xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/volume"1305"xsd:string
http://purl.uniprot.org/citations/8605245http://purl.uniprot.org/core/volume"1305"xsd:string
http://purl.uniprot.org/citations/8605245http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8605245
http://purl.uniprot.org/citations/8605245http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8605245
http://purl.uniprot.org/citations/8605245http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8605245
http://purl.uniprot.org/citations/8605245http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8605245