http://purl.uniprot.org/citations/8607800 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8607800 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8607800 | http://www.w3.org/2000/01/rdf-schema#comment | "The ATP-sensitive potassium channel of insulin-secreting pancreatic beta-cells is a complex of Kir6.2, a member of the inwardly rectifying potassium channel superfamily, and the sulfonylurea receptor. We have isolated cDNA clones encoding rat Kir6.2. Co-expression of rat Kir6.2 and sulfonylurea receptor in human embryonic kidney cells generated a potassium current with the properties of the beta-cell ATP-sensitive potassium channel. A quantitative reverse transcriptase-polymerase chain reaction assay indicated that Kir6.2 and sulfonylurea receptor mRNAs were abundantly expressed in rat islets and that expression of Kir6.2 mRNA was reduced by >70% in islets from Zucker diabetic fatty male rats, whereas there was no significant change in sulfonylurea receptor mRNA levels. Thus, decreased expression of Kir6.2 could contribute to the beta-cell dysfunction which characterizes diabetes mellitus in this animal model."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1996.0439"xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1996.0439"xsd:string |
http://purl.uniprot.org/citations/8607800 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8607800 |
http://purl.uniprot.org/citations/8607800 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8607800 |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Bell G.I."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Bell G.I."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Fan Z."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Fan Z."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Furuta H."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Furuta H."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Yano H."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Yano H."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Tokuyama Y."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Tokuyama Y."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Polonsky K.S."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Polonsky K.S."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Makielski J.C."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/author | "Makielski J.C."xsd:string |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8607800 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |