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http://purl.uniprot.org/citations/8612769http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8612769http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8612769http://www.w3.org/2000/01/rdf-schema#comment"KV,Ca beta subunit dramatically increases the apparent calcium sensitivity of the alpha subunit of MaxiK channels when probed in the micromolar [Ca2+]i range. Analysis in a wide range of [Ca2+]i revealed that this functional coupling is exquisitely modulated by [Ca2+]i. Ca2+ ions switch MaxiK alpha+beta complex into a functionally coupled state at concentrations beyond resting [Ca2+]i. At [Ca2+] < or = 100 nM, MaxiK activity becomes independent of Ca2+, is purely voltage-activated, and its functional coupling with its beta subunit is released. The functional switch develops at [Ca2+]i that occur during cellular excitation, providing the molecular basis of how MaxiK channels regulate smooth muscle excitability and neurotransmitter release."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.org/dc/terms/identifier"doi:10.1016/0014-5793(96)00151-2"xsd:string
http://purl.uniprot.org/citations/8612769http://purl.org/dc/terms/identifier"doi:10.1016/0014-5793(96)00151-2"xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/author"Jiang Z."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/author"Jiang Z."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/author"Wallner M."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/author"Wallner M."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/author"Toro L."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/author"Toro L."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/author"Meera P."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/author"Meera P."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/pages"84-88"xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/pages"84-88"xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/title"A calcium switch for the functional coupling between alpha (hslo) and beta subunits (KV,Ca beta) of maxi K channels."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/title"A calcium switch for the functional coupling between alpha (hslo) and beta subunits (KV,Ca beta) of maxi K channels."xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/volume"382"xsd:string
http://purl.uniprot.org/citations/8612769http://purl.uniprot.org/core/volume"382"xsd:string
http://purl.uniprot.org/citations/8612769http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8612769
http://purl.uniprot.org/citations/8612769http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8612769