http://purl.uniprot.org/citations/8621702 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8621702 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8621702 | http://www.w3.org/2000/01/rdf-schema#comment | "The ability of activating transcription factor-1 (ATF1) or the cAMP response element-binding protein (CREB) to enhance transcription can be stimulated by increases in intracellular Ca2+ concentrations. To identify protein kinases which may mediate the ability of Ca2+ to activate these transcription factors, we compared the ability of constitutively active forms of several Ca2+/calmodulin-dependent protein kinases (CaM kinases) to activate ATF1 or CREB. We find that constitutively active CaM kinase I and IV can activate both ATF1 and CREB. In addition, expression vectors for full-length CaM kinase I and IV were able to augment the ability of Ca2+ influx to activate ATF1 or CREB consistent with a role for these kinases in mediating transcriptional responses to Ca2+ signaling. In contrast, CaM kinase II was unable to activate either ATF1 or CREB. These findings provide a potential mechanism that may permit variation in the ability of ATF1 and CREB to respond to changes in intracellular Ca2+ concentrations depending on differences in the relative concentrations of specific CaM kinases."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.271.6.3066"xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.271.6.3066"xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/author | "Lou L."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/author | "Lou L."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/author | "Sun P."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/author | "Sun P."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/author | "Maurer R.A."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/author | "Maurer R.A."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/pages | "3066-3073"xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/pages | "3066-3073"xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/title | "Regulation of activating transcription factor-1 and the cAMP response element-binding protein by Ca2+/calmodulin-dependent protein kinases type I, II, and IV."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/title | "Regulation of activating transcription factor-1 and the cAMP response element-binding protein by Ca2+/calmodulin-dependent protein kinases type I, II, and IV."xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/volume | "271"xsd:string |
http://purl.uniprot.org/citations/8621702 | http://purl.uniprot.org/core/volume | "271"xsd:string |
http://purl.uniprot.org/citations/8621702 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8621702 |
http://purl.uniprot.org/citations/8621702 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8621702 |
http://purl.uniprot.org/citations/8621702 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8621702 |
http://purl.uniprot.org/citations/8621702 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8621702 |