| http://purl.uniprot.org/citations/8625762 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8625762 | http://www.w3.org/2000/01/rdf-schema#comment | "A specific plasma kallikrein inhibitor, Bz-Pro-Phe-boroArg (P8720), was used to define the relationship between the kallikrein-kinin (K-K) system and acute intestinal inflammation induced by bacterial peptidoglycan-polysaccharide (PG-APS) in Lewis rats. Group I received human serum albumin (HSA) intramurally in the intestine and was treated with HSA. Group II received PG-APS and was treated with P8720. Group III received PG-APS and was treated with HSA. P8720 attenuated the decrease of high-molecular-weight kininogen and factor XI activity (group II vs group III, P < 0.01). P8720 therapy significantly but modestly decreased acute intestinal inflammation measured by gross gut score (P < 0.01) and more dramatically reduced the tissue myeloperoxidase activity (P < 0.05), a measure of granulocyte recruitment, in group II compared with group III. We conclude that the K-K system is directly involved in the pathogenesis of the acute phase of experimental acute inflammation. A specific inhibitor may modulate inflammatory bowel disease."xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf02091530"xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/author | "Kettner C.A."xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/author | "Sartor R.B."xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/author | "Bender D."xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/author | "Colman R.W."xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/author | "Adam A."xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/author | "DeLa Cadena R.A."xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/author | "Rath H.C."xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/author | "Stadnicki A."xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/name | "Dig Dis Sci"xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/pages | "912-920"xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/title | "Selective plasma kallikrein inhibitor attenuates acute intestinal inflammation in Lewis rat."xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://purl.uniprot.org/core/volume | "41"xsd:string |
| http://purl.uniprot.org/citations/8625762 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8625762 |
| http://purl.uniprot.org/citations/8625762 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8625762 |
| http://purl.uniprot.org/uniprot/#_P14272-mappedCitation-8625762 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8625762 |
| http://purl.uniprot.org/uniprot/P14272 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/8625762 |