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http://purl.uniprot.org/citations/8626462http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8626462http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8626462http://www.w3.org/2000/01/rdf-schema#comment"We have cloned a novel cDNA from human brain which encodes a non-voltage-dependent Na+ channel (BNC1). BNC1 has some sequence similarity (24-28%) with a new channel family that includes subunits of the mammalian epithelial Na+ channel, the Caenorhabditis elegans degenerins, and the Helix aspersa FMRF-amide-gated Na+ channel. Like other family members it is inhibited by amiloride. However, its predicted structure differs from other family members, its discrimination between Na+ and Li+ is different, and in contrast to other mammalian family members, coexpression with other cloned subunits of the family does not increase current. BNC1 has a unique pattern of expression with transcripts detected only in adult human brain and in spinal cord. Thus, BNC1 is the first cloned member of a new subfamily of mammalian Na+ channels. The function of BNC1 as a non-voltage-gated Na+ channel in human brain suggests it may play a novel role in neurotransmission."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.org/dc/terms/identifier"doi:10.1074/jbc.271.14.7879"xsd:string
http://purl.uniprot.org/citations/8626462http://purl.org/dc/terms/identifier"doi:10.1074/jbc.271.14.7879"xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/author"Welsh M.J."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/author"Welsh M.J."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/author"Price M.P."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/author"Price M.P."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/author"Snyder P.M."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/author"Snyder P.M."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/pages"7879-7882"xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/pages"7879-7882"xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/title"Cloning and expression of a novel human brain Na+ channel."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/title"Cloning and expression of a novel human brain Na+ channel."xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/volume"271"xsd:string
http://purl.uniprot.org/citations/8626462http://purl.uniprot.org/core/volume"271"xsd:string
http://purl.uniprot.org/citations/8626462http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8626462
http://purl.uniprot.org/citations/8626462http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8626462
http://purl.uniprot.org/citations/8626462http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8626462
http://purl.uniprot.org/citations/8626462http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8626462