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http://purl.uniprot.org/citations/8630005http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8630005http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8630005http://www.w3.org/2000/01/rdf-schema#comment"Sets of degenerate oligonucleotide primers synthesized on the basis of the best conserved regions of the chick brain P2Y/P2Y1 and the murine neuroblastoma P2U/P2Y2 receptors were used in polymerase chain reaction experiments on human genomic DNA. An amplified fragment of 712 base pairs was then used as a probe to screen a human genomic DNA library. Several clones were isolated and sequencing revealed an intronless 1122 base pair open reading frame. The corresponding amino acid sequence revealed 83% identity with the chick brain P2Y1 receptor and 34% with the murine neuroblastoma P2Y2 receptor. In COS-7 cells transfected with the coding sequence inserted into the pcDNA3 expression vector, 2-methylthioATP and ATP produced a strong stimulation of inositol phosphates, a typical response of a P2Y1 receptor. Northern blot analysis detected a 6.7 kilobase messenger RNA in most human tissues, the strongest signals being observed in prostate and ovary."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1996.0640"xsd:string
http://purl.uniprot.org/citations/8630005http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1996.0640"xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Parmentier M."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Parmentier M."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Samson M."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Samson M."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Communi D."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Communi D."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Janssens R."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Janssens R."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Boeynaems J.-M."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Boeynaems J.-M."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Pirotton S."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/author"Pirotton S."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/pages"588-593"xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/pages"588-593"xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/title"Cloning and tissue distribution of the human P2Y1 receptor."xsd:string
http://purl.uniprot.org/citations/8630005http://purl.uniprot.org/core/title"Cloning and tissue distribution of the human P2Y1 receptor."xsd:string