| http://purl.uniprot.org/citations/8641685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8641685 | http://www.w3.org/2000/01/rdf-schema#comment | "We examined a Ser-9-Gly polymorphism in the dopamine D3 receptor gene for allelic association with schizophrenia in 133 patients currently treated with clozapine and 109 controls. Allele 1 (Ser-9) was significantly more frequent in the patients (69%) than in the controls (56%) (P = 0.004). The 1-1 genotype was more common (43% vs 30%) and the 2-2 genotype less common (5% vs 18%) in patients than in controls. When the patient group was subdivided on the basis of clinical response to clozapine, using a 20-point improvement in the global assessment scale as cut-off, genotype 1-1 was found to be more frequent among the non-responders (53% vs 36%, P = 0.04). To place our results in the context of previous studies of this polymorphism and schizophrenia, we performed a meta-analysis of all published data including the present sample. The combined analysis shows evidence for a modest association between genotype 1-1 and schizophrenia (odds ratio 1.25, 95% confidence interval 1.05-1.49, P = 0.01). These results suggest that the Ser-9 allele, or a nearby polymorphism in linkage disequilibrium, results in a small increase in susceptibility to schizophrenia."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf02346178"xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/author | "Vallada H."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/author | "Smith I."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/author | "Gill M."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/author | "Collier D.A."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/author | "Sham P.C."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/author | "Shaikh S."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/author | "Kerwin R.W."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/author | "Ball D."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/author | "Aitchison K."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/name | "Hum Genet"xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/pages | "714-719"xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/title | "Allelic association between a Ser-9-Gly polymorphism in the dopamine D3 receptor gene and schizophrenia."xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://purl.uniprot.org/core/volume | "97"xsd:string |
| http://purl.uniprot.org/citations/8641685 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8641685 |
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| http://purl.uniprot.org/uniprot/#_A8K8E4-mappedCitation-8641685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8641685 |
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| http://purl.uniprot.org/uniprot/#_P35462-mappedCitation-8641685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8641685 |
| http://purl.uniprot.org/uniprot/#_Q9BXX6-mappedCitation-8641685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8641685 |