| http://purl.uniprot.org/citations/8643484 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8643484 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8643484 | http://www.w3.org/2000/01/rdf-schema#comment | "The translocation t(10;11)(p13;q14) is a recurring chromosomal abnormality that has been observed in patients with acute lymphoblastic leukemia as well as acute myeloid leukemia. We have recently reported that the monocytic cell line U937 has a t(10;11)(p13;q14) translocation. Using a combination of positional cloning and candidate gene approach, we cloned the breakpoint and were able to show that AF10 is fused to a novel gene that we named CALM (Clathrin Assembly Lymphoid Myeloid leukemia gene) located at 11q14. AF10, a putative transcription factor, had recently been cloned as one of the fusion partners of MLL. CALM has a very high homology in its N-terminal third to the murine ap-3 gene which is one of the clathrin assembly proteins. The N-terminal region of ap-3 has been shown to bind to clathrin and to have a high-affinity binding site for phosphoinositols. The identification of the CALM/AF10 fusion gene in the widely used U937 cell line will contribute to our understanding of the malignant phenotype of this line."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.93.10.4804"xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.93.10.4804"xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Zheng M."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Zheng M."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Mao J."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Mao J."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Rowley J.D."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Rowley J.D."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Bohlander S.K."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Bohlander S.K."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Martinez-Climent J.A."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Martinez-Climent J.A."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Dreyling M.H."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/author | "Dreyling M.H."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/pages | "4804-4809"xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/pages | "4804-4809"xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/title | "The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family."xsd:string |
| http://purl.uniprot.org/citations/8643484 | http://purl.uniprot.org/core/title | "The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family."xsd:string |