| http://purl.uniprot.org/citations/8648092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8648092 | http://www.w3.org/2000/01/rdf-schema#comment | "NK cells express cell surface receptors for MHC class I proteins (KIR). Engagement of these receptors inhibits NK cell cytotoxic programs. KIR can be expressed on T cells, and their engagement also results in inhibition of effector functions initiated by the CD3/TCR complex. While human KIR genes belong to the Ig gene superfamily, mouse KIR belong to a family of dimeric lectins. Despite these distinct evolutionary origins, we show here that both HLA-Cw3-specific human p58.183 receptors and H-2D d/k-specific mouse Ly49A receptors recruit the same protein tyrosine phosphatases, PTP1C and PTP1D, upon phosphorylation of critical intracytoplasmic tyrosine residues. These results document a common pathway by which diverse KIR can down-regulate NK and T cell activation programs, and further define the sequence of the immunoreceptor tyrosine-based inhibitory motif (ITIM), initially described in FcgammaRIIB1, and expressed in both human and mouse KIR."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Marguet D."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Lang P."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Moretta L."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Biassoni R."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Cambier J.C."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Moretta A."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Vivier E."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Vely F."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Blery M."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Cambiaggi A."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Olcese L."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/author | "Hippen K.L."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/pages | "4531-4534"xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/title | "Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases."xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://purl.uniprot.org/core/volume | "156"xsd:string |
| http://purl.uniprot.org/citations/8648092 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8648092 |
| http://purl.uniprot.org/citations/8648092 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8648092 |
| http://purl.uniprot.org/uniprot/#_Q06124-mappedCitation-8648092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8648092 |
| http://purl.uniprot.org/uniprot/#_P20963-mappedCitation-8648092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8648092 |
| http://purl.uniprot.org/uniprot/#_P29350-mappedCitation-8648092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8648092 |
| http://purl.uniprot.org/uniprot/#_P43403-mappedCitation-8648092 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8648092 |