http://purl.uniprot.org/citations/8648744 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8648744 | http://www.w3.org/2000/01/rdf-schema#comment | "The murine retrovirus SL3-3 is a potent inducer of T-cell lymphomas when inoculated into susceptible newborn mice. The proviral integration site sequences were surveyed in tumor DNAs by a simple two-step PCR method. From 20 SL3-3-induced tumors a total of 39 provirus-host junctions were amplified and sequenced. Seven showed homology to known sequences. These included the known common integration site c-myc as well as genes not previously identified as targets of provirus integration, namely N-ras and the genes coding for major histocompatibility complex class 11 E-beta, protein kinase C-eta, and T-cell receptor beta-chain. Among these genes, the integrations in c-myc as well as the one in N-ras were found to be clonal. One of the remaining 32 proviral integration site sequences that show no similarities to known sequences may represent a common integration site, as 2 of the 20 tumors demonstrated clonal provirus insertion into this region."xsd:string |
http://purl.uniprot.org/citations/8648744 | http://purl.org/dc/terms/identifier | "doi:10.1128/jvi.70.6.4063-4070.1996"xsd:string |
http://purl.uniprot.org/citations/8648744 | http://purl.uniprot.org/core/author | "Jorgensen P."xsd:string |
http://purl.uniprot.org/citations/8648744 | http://purl.uniprot.org/core/author | "Pedersen F.S."xsd:string |
http://purl.uniprot.org/citations/8648744 | http://purl.uniprot.org/core/author | "Amtoft H.W."xsd:string |
http://purl.uniprot.org/citations/8648744 | http://purl.uniprot.org/core/author | "Sorensen A.B."xsd:string |
http://purl.uniprot.org/citations/8648744 | http://purl.uniprot.org/core/author | "Duch M."xsd:string |
http://purl.uniprot.org/citations/8648744 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8648744 | http://purl.uniprot.org/core/name | "J Virol"xsd:string |
http://purl.uniprot.org/citations/8648744 | http://purl.uniprot.org/core/pages | "4063-4070"xsd:string |
http://purl.uniprot.org/citations/8648744 | http://purl.uniprot.org/core/title | "Sequence tags of provirus integration sites in DNAs of tumors induced by the murine retrovirus SL3-3."xsd:string |
http://purl.uniprot.org/citations/8648744 | http://purl.uniprot.org/core/volume | "70"xsd:string |
http://purl.uniprot.org/citations/8648744 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8648744 |
http://purl.uniprot.org/citations/8648744 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8648744 |
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