| http://purl.uniprot.org/citations/8649400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8649400 | http://www.w3.org/2000/01/rdf-schema#comment | "B-lymphocyte development requires the basic helix-loop-helix proteins encoded by the E2A gene. In this study, the control mechanism of E2A was further explored by disruption of the E2A-related genes, E2-2 and HEB. In contrast to E2A, E2-2 and HEB are not essential for the establishment of the B-cell lineage. However, both E2-2 and HEB are required for the generation of the normal numbers of pro-B cells in mouse embryos. Breeding tests among mice carrying different mutations revealed that E2-2 and HEB interact with E2A in many developmental processes including generation of B cells. Specifically, mice transheterozygous for any two mutations of these three genes produced fewer pro-B cells than the singly heterozygous littermates. This study indicates that B-cell development is dependent not only on an essential function provided by the E2A gene but also on a combined dosage set by E2A, E2-2, and HEB."xsd:string |
| http://purl.uniprot.org/citations/8649400 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.16.6.2898"xsd:string |
| http://purl.uniprot.org/citations/8649400 | http://purl.uniprot.org/core/author | "Cheng P."xsd:string |
| http://purl.uniprot.org/citations/8649400 | http://purl.uniprot.org/core/author | "Weintraub H."xsd:string |
| http://purl.uniprot.org/citations/8649400 | http://purl.uniprot.org/core/author | "Zhuang Y."xsd:string |
| http://purl.uniprot.org/citations/8649400 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8649400 | http://purl.uniprot.org/core/name | "Mol Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/8649400 | http://purl.uniprot.org/core/pages | "2898-2905"xsd:string |
| http://purl.uniprot.org/citations/8649400 | http://purl.uniprot.org/core/title | "B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB."xsd:string |
| http://purl.uniprot.org/citations/8649400 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/8649400 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8649400 |
| http://purl.uniprot.org/citations/8649400 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8649400 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YTR9-mappedCitation-8649400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8649400 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YTU7-mappedCitation-8649400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8649400 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YTW1-mappedCitation-8649400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8649400 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YTX3-mappedCitation-8649400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8649400 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YU37-mappedCitation-8649400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8649400 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YU75-mappedCitation-8649400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8649400 |
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| http://purl.uniprot.org/uniprot/#_A0A0J9YU91-mappedCitation-8649400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8649400 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YU99-mappedCitation-8649400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8649400 |
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| http://purl.uniprot.org/uniprot/#_A0A0J9YUK1-mappedCitation-8649400 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8649400 |