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http://purl.uniprot.org/citations/8650580http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8650580http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8650580http://www.w3.org/2000/01/rdf-schema#comment"ZPR1 is a zinc finger protein that binds to the cytoplasmic tyrosine kinase domain of the epidermal growth factor receptor (EGFR). Deletion analysis demonstrated that this binding interaction is mediated by the zinc fingers of ZPR1 and subdomains X and XI of the EGFR tyrosine kinase. Treatment of mammalian cells with EGF caused decreased binding of ZPR1 to the EGFR and the accumulation of ZPR1 in the nucleus. The effect of EGF to regulate ZPR1 binding is dependent on tyrosine phosphorylation of the EGFR. ZPR1 therefore represents a prototype for a class of molecule that binds to the EGFR and is released from the receptor after activation."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.org/dc/terms/identifier"doi:10.1126/science.272.5269.1797"xsd:string
http://purl.uniprot.org/citations/8650580http://purl.org/dc/terms/identifier"doi:10.1126/science.272.5269.1797"xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Barrett T."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Barrett T."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Davis R.J."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Davis R.J."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Galcheva-Gargova Z."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Galcheva-Gargova Z."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Klier F.G."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Klier F.G."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Konstantinov K.N."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Konstantinov K.N."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Wu I.-H."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/author"Wu I.-H."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/pages"1797-1802"xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/pages"1797-1802"xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/title"Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor."xsd:string
http://purl.uniprot.org/citations/8650580http://purl.uniprot.org/core/title"Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor."xsd:string