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| http://purl.uniprot.org/citations/8654595 | http://www.w3.org/2000/01/rdf-schema#comment | "Trihydroxycoprostanoyl-CoA oxidase and pristanoyl-CoA oxidase, purified from rat liver, both catalyse the desaturation of 2-methyl-branched acyl-CoAs. Upon incubation with the pure isomers of 2-methylpentadecanoyl-CoA, both enzymes acted only on the S-isomer. The R-isomer inhibited trihydroxycoprostanoyl-CoA oxidase but did not affect pristanoyl-CoA oxidase. The activity of both enzymes was suppressed by 3-methylheptadecanoyl-CoA. Valproyl-CoA and 2-ethylhexanoyl-CoA, however, did not influence the oxidases. Although only one isomer of 25R,S-trihydroxycoprostanovl-CoA was desaturated by trihydroxycoprostanoyl-CoA oxidase, isolated peroxisomes were able to act on both isomers, suggesting the presence of a racemase in these organelles. Given the opposite stereoselectivity of the 26-cholesterol hydroxylase and of the oxidase, the racemase is essential for bile acid formation."xsd:string |
| http://purl.uniprot.org/citations/8654595 | http://purl.org/dc/terms/identifier | "doi:10.1016/0014-5793(96)00508-x"xsd:string |
| http://purl.uniprot.org/citations/8654595 | http://purl.uniprot.org/core/author | "Herdewijn P."xsd:string |
| http://purl.uniprot.org/citations/8654595 | http://purl.uniprot.org/core/author | "Van Veldhoven P.P."xsd:string |
| http://purl.uniprot.org/citations/8654595 | http://purl.uniprot.org/core/author | "Mannaerts G.P."xsd:string |
| http://purl.uniprot.org/citations/8654595 | http://purl.uniprot.org/core/author | "Asselberghs S."xsd:string |
| http://purl.uniprot.org/citations/8654595 | http://purl.uniprot.org/core/author | "Croes K."xsd:string |
| http://purl.uniprot.org/citations/8654595 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8654595 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/8654595 | http://purl.uniprot.org/core/pages | "80-84"xsd:string |
| http://purl.uniprot.org/citations/8654595 | http://purl.uniprot.org/core/title | "Peroxisomal beta-oxidation of 2-methyl-branched acyl-CoA esters: stereospecific recognition of the 2S-methyl compounds by trihydroxycoprostanoyl-CoA oxidase and pristanoyl-CoA oxidase."xsd:string |
| http://purl.uniprot.org/citations/8654595 | http://purl.uniprot.org/core/volume | "388"xsd:string |
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