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http://purl.uniprot.org/citations/8655503http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8655503http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8655503http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8655503http://www.w3.org/2000/01/rdf-schema#comment"The plasmid pGT5 (3,444 bp) from the hyperthermophilic archaeon Pyrococcus abyssi GE5 has been completely sequenced. Two major open reading frames with a good coding probability are located on the same strand and cover 85% of the total sequence. The larger open reading frame encodes a putative polypeptide which exhibits sequence similarity with Rep proteins of plasmids using the rolling-circle mechanism for replication. Upstream of this open reading frame, we have detected an 11-bp motif identical to the double-stranded origin of several bacterial plasmids that replicate via the rolling-circle mechanism. A putative single-stranded origin exhibits similarities both to bacterial primosome-dependent single-stranded initiation sites and to bacterial primase (dnaG) start sites. A single-stranded form of pGT5 corresponding to the plus strand was detected in cells of P. abyssi. These data indicate that pGT5 replicates via the rolling-circle mechanism and suggest that members of the domain Archaea contain homologs of several bacterial proteins involved in chromosomal DNA replication. Phylogenetic analysis of Rep proteins from rolling-circle replicons suggest that diverse families diverged before the separation of the domains Archaea, Bacteria, and Eucarya."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.org/dc/terms/identifier"doi:10.1128/jb.178.11.3232-3237.1996"xsd:string
http://purl.uniprot.org/citations/8655503http://purl.org/dc/terms/identifier"doi:10.1128/jb.178.11.3232-3237.1996"xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Barbeyron T."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Barbeyron T."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Barbeyron T."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Erauso G."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Erauso G."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Erauso G."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Forterre P."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Forterre P."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Forterre P."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Zivanovic Y."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Zivanovic Y."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Zivanovic Y."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Prieur D."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Prieur D."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Prieur D."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Marsin S."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Marsin S."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Marsin S."xsd:string
http://purl.uniprot.org/citations/8655503http://purl.uniprot.org/core/author"Baucher M.F."xsd:string