| http://purl.uniprot.org/citations/8668157 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8668157 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8668157 | http://www.w3.org/2000/01/rdf-schema#comment | "We cloned the Schizosaccharomyces pombe map1 gene by virtue of its ability to stimulate transcription of the sxa2 gene, which encodes a carboxypeptidase expressed specifically in h-cells in response to mating-pheromone signaling. The cloned gene had a coding capacity of 398 amino acids split by two introns, and the deduced product was a protein of the MADS box family. This gene was most similar to Saccharomyces cerevisiae MCM1, which regulates cell-type-specific gene expression in budding yeast cells. Disruption of the S. pombe gene did not affect vegetative cell growth but conferred sterility. It blocked the mating ability of h+ cells completely and that of h-cells partially. Genetic and sequencing analysis indicated that the cloned gene is map1], which was originally defined by a mutation that caused h+-speciftic sterility. Northern (RNA) blot analysis showed that the function of map1 is absolutely essential for the expression of h+-specific genes and is required for the full activation of h--specific gene expression. Overexpression of map1 resulted in enhanced transcription of cell-type-specilic genes, but the range of genes affected by Map1 was restricted by the mating type of the cell. Results of yeast two-hybrid analysis suggested that Map1 may physically interact with Mat1-Pc, the product of the h(+)-specific mating-type gene mat1-Pc. On the basis of these observations, we speculate that Map1 may be a transcriptional regulator of cell-type-specific genes similar to S. cerevisiae MCM1, whose activity is modulated by the oil and alpha2 mating-type gene products."xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.16.7.3420"xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.16.7.3420"xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/author | "Yamamoto M."xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/author | "Yamamoto M."xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/author | "Yabana N."xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/author | "Yabana N."xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/pages | "3420-3428"xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/pages | "3420-3428"xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/title | "Schizosaccharomyces pombe map1+ encodes a MADS-box-family protein required for cell-type-specific gene expression."xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/title | "Schizosaccharomyces pombe map1+ encodes a MADS-box-family protein required for cell-type-specific gene expression."xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/8668157 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8668157 |
| http://purl.uniprot.org/citations/8668157 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8668157 |
| http://purl.uniprot.org/citations/8668157 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8668157 |
| http://purl.uniprot.org/citations/8668157 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8668157 |
| http://purl.uniprot.org/uniprot/P78926 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/8668157 |
| http://purl.uniprot.org/uniprot/P10841#attribution-043E162BE01096DEA1C5694D9596D69E | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/8668157 |