http://purl.uniprot.org/citations/8683207 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8683207 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8683207 | http://www.w3.org/2000/01/rdf-schema#comment | "The complete nucleotide sequence of a human T-cell lymphotropic virus type II isolate (HTLV-II-Gu) from an Italian injecting drug user was obtained, representing the first entire sequence of a European HTLV-II isolate. The HTLV-II-Gu genome was more similar to the HTLV-IIb-NRA isolate (98.4%) and HTLV-IIb-G12 (98.2%) than to HTLV-IIa-Mo (95.2%). The classification of HTLV-II-Gu as subtype IIb was confirmed by restriction analysis. Just as for HTLV-IIa strain Mo, HTLV-IIb-Gu cultured lymphocytes produce two additional mRNAs generated through alternative splicing in the pX region. A phylogenetic analysis was performed by using the methods of neighbour-joining and parsimony with bootstrapping, and maximum likelihood. The different gene regions were analysed separately, comparing Gu with all other HTLV-II strains presently available. In the LTR, as well as in other genome regions, a clear separation between IIa and IIb was evident, and within the IIb subtype three clusters were present of which two were well supported; one contained exclusively Amerindian strains and the other included all Italian and Spanish strains together with two strains obtained from New York drug users. All data clearly showed that HTLV-IIa and IIb subtypes are closely related and are equidistant from HTLV-I, suggesting that both groups evolved simultaneously. The results suggest that HTLV-II-Gu and other IIb South European isolates were probably derived from North American IIb isolates. The data also indicate that sequence analysis is necessary to further classify IIa and IIb subtypes."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.org/dc/terms/identifier | "doi:10.1099/0022-1317-77-6-1193"xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Salemi M."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Salemi M."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Bertazzoni U."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Bertazzoni U."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Vandamme A.M."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Vandamme A.M."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Cattaneo E."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Cattaneo E."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Casoli C."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Casoli C."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Gradozzi C."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Gradozzi C."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Guano F."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/author | "Guano F."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/name | "J. Gen. Virol."xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/name | "J Gen Virol"xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/pages | "1193-1201"xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/pages | "1193-1201"xsd:string |
http://purl.uniprot.org/citations/8683207 | http://purl.uniprot.org/core/title | "omplete nucleotide sequence of the Italian human T-cell lymphotropic virus type II isolate Gu and phylogenetic identification of a possible origin of South European epidemics."xsd:string |