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http://purl.uniprot.org/citations/8710854http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8710854http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8710854http://www.w3.org/2000/01/rdf-schema#comment"Tumor necrosis factor (TNF) receptor-associated factor (TRAF) proteins associate with and transduce signals from TNF receptor 2, CD40, and presumably other members of the TNF receptor superfamily. TRAF2 is required for CD40- and TNF-mediated activation of the transcription factor NF-kappa B. Here we describe the isolation and characterization of a novel TRAF-interacting protein, I-TRAF, that binds to the conserved TRAF-C domain of the three known TRAFs. Overexpression of I-TRAF inhibits TRAF2-mediated NF-kappa B activation signaled by CD40 and both TNF receptors. Thus, I-TRAF appears as a natural regulator of TRAF function that may act by maintaining TRAFs in a latent state."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.org/dc/terms/identifier"doi:10.1073/pnas.93.16.8241"xsd:string
http://purl.uniprot.org/citations/8710854http://purl.org/dc/terms/identifier"doi:10.1073/pnas.93.16.8241"xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Xiong J."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Xiong J."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Rothe M."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Rothe M."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Goddard A."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Goddard A."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Goeddel D.V."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Goeddel D.V."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Williamson K."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Williamson K."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Shu H.-B."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/author"Shu H.-B."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/pages"8241-8246"xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/pages"8241-8246"xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/title"I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction."xsd:string
http://purl.uniprot.org/citations/8710854http://purl.uniprot.org/core/title"I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction."xsd:string